Amy Jenne

Ph.D. | Assistant Professor, Teaching Stream | Chemistry | Analytical Chemistry

E-mail:

amy.jenne@mail.utoronto.ca
Mailing Address:

3359 Mississauga Road
Mississauga ON L5L1C6
Canada

Research Areas:

Environmental Chemistry, Nuclear Magnetic Resonance Spectroscopy, Metabolomics, Community-Engaged Learning, Student Metacognition

Research Profile:

My Ph.D. research focused on examining metabolic changes (changes to the low molecular weight components in a living system) in Daphnia magna (water fleas) using Nuclear Magnetic Resonance Spectroscopy (NMR). In this work I created a variety of new techniques to help examine small changes while overcoming the current sensitivity limitations in NMR. Overall, the work informs us about how the chemicals we are exposed to in the water impact our critical systems. However, through my graduate studies I also engaged with pedagogical research on a variety of topics including creating more accessible laboratory experiments and hardware for students with disabilities, helping develop students metacognitive practices and study strategies, and engaging in community-engaged learning in the undergraduate chemistry classroom. I even combined my research and pedagogical interests to create a new analytical low-field NMR experiment.

I am excited to be joining the department and I would like to continue to develop community-engaged learning practices in the undergraduate classroom, specifically in an analytical setting. My hope is to expand student’s understanding of how chemistry can be used outside the classroom by partnering with community groups who will challenge students to solve content-related problems.

Courses Taught:

CHM211H5, CHM416H5, JCP422H5

Publications

Ronda, K.; Downey, K.; Jenne, A.; Bastawrous, M.; Wolff, W.W.; Steiner, K.; Lysak, D.H.; Costa, P.M.; Simpson, M.J.; Jobst, K.; Simpson, A.J. Exploring proton-only NMR experiments and filters for daphnia in-vivo: Potential and limitations. Molecules. 2023, 28(12), 4863.

Jenne, A.; von der Ecken, S.; Moxley-Paquette, V.; Soong, R.; Swyer, I.; Bastawrous, M.; Busse, F.; Bermel, W.; Schmidig, D.; Kuehn, T.; Keummerle, R.; Al Adwan-Stojilkovic, D.; Graf, S.; Frei, T.; Monette, M.; Wheeler, A.R.; Simpson, A.J. Integrated digital microfuidics NMR spectroscopy: A key step towards automated in-vivo metabolomics. Analytical Chemistry. 2023, 95(14), 5858-5866.

Downey, K.; Michal, C.; Bermel , W.; Jenne, A.; Soong, R.; Decker, V.; Busse, F.; Goerling, B.; Heumann, H.; Boenisch, H.; Gundy, M.; Simpson, A. Targeted compound selection with increased sensitivity in ¹³C enriched biological and environmental samples using ¹³C-DREAMTIME in both high-field and low-field NMR. Analytical Chemistry. 2023, 96(16), 6709-6717.

Ghosh Biswas, R.; Soong, R.; Jenne, A.; Bastawrous, M.; Simpson, M.; Simpson, A. SASSY. NMR: Simultaneous solid and solution spectroscopy. Angewante Chemie International Edition. 2023, 62(8), e202216105.

Jenne, A.; Soong, R.; Gruschke, O.; Bastawrous, M.; Monks, P.; Moloney, C.; Brougham, D.F.; Busse, F.; Bermel, W.; Courtier-Murias, D.; Wu, B.; Simpson, A. A holistic NMR framework to understand environmental impact: Examining the impacts of superparamagnetic iron oxide nanoparticles (SPIONs) in Daphnia magna via imaging, spectroscopy, and metabolomics. Magnetic Resonance in Chemistry. 2022.

Soong, R.; Downey, K.; Moser, A.; Monje, P.; Jenne, A.; Ghosh Biswas, R.; Bastawrous, M.; Majumdar, R.; Lysak, D.; Adamo, A.; Goerling, B.; Decker, V.; Busse, F.; Dominguez, S.; Sauer, E.; Mikhaylichenko, S.; Luk, V.; Simpson, A. A CASE (computer-assisted structure elucidation) for bench-top NMR systems in the undergraduate laboratory for de novo structure determination: How well can we do? Journal of Chemical Education. 2022, 99(11), 3780-3788.

Ghosh Biswas, R.; Soong, R.; Ning, P.; Lane, D.; Bastawrous, M.; Jenne, A.; Schmidig, D.; de Castro, P.; Graf, S.; Kuehn, T.; Kummerle, R.; Bermel, W.; Busse, F.; Struppe, J.; Simpson, M.J.; Simpson, A.J. Exploring the applications of carbon-detected NMR in living and dead organisms using a 13C-optimized comprehensive multiphase NMR probe. Analytical Chemistry. 2022, 94(24), 8756-8765.

Bastawrous, M.; Gruschke, O.; Soong, R.; Jenne, A.; Gross, D.; Busse, F.; Nashman, B.; Lacerda, A.; Simpson. A.J. Comparing the potential of helmholtz and planar NMR microcoils for analysis of intact biological samples. Analytical Chemistry. 2022, 94(23), 8523-8532.

Jenne, A.; Bermel, W.; Gruschke, O.; Soong, R.; Ghosh Biswas, R.; Bastawrous, M.; Simpson, A. DREAMTIME NMR spectroscopy: Targeted multi-compound selection with improved detection limits. Angewandte Chemie International Edition. 2022, 61(19), e202110044.

Ning, P.; Lane, D.; Ghosh Biswas, R.; Jenne, A.; Soong, R.; Schmidig, D.; Frei, T.; de Castro, P.; Kovacevic, I.; Graf, S.; Wegner, S.; Bermel, W.; Busse, F.; Kuehn, F.; Kuemmerle, R.; Struppe, J.; Fey, M.; Stronks, H.; Monette, M.; Simpson, M.; Simpson, A. Expanding current applications and permitting the analysis of larger intact samples by means of a 7 mm CMP-NMR probe. Analyst. 2021, 14(6), 4461-4472.

O'Reilly, S.S.; Jordan, S.F.; Monteys, X.; Simpson, A.J.; Allen, C.R.R.; Szpak, M.T.; Murphy, B.T.; Mc-Carron, S.G.; Soong, R.; Wu, B.; Jenne, A.; Grey, A.; Kelleher, B.P. Production of methane and gaseous compounds by surface microbial activity in a small pockmark field, Dunmanus Bay, Ireland. Estuarine, Coastal, and Shelf Science. 2021, 255, 107340.

Soong, R.; Jenne, A.; Lysak, D.; Ghosh Biswas, R.; Adamo, A.; Kim, K.; Ma, Yiyi.; Simpson, A. Titrate from home over the internet: Overcoming social distancing via an opensource remote control titration unit. Journal of Chemical Education. 2021, 98(3), 1037-1042.

Tian, Z.; Zhao, H.; Peter, K.T.; Gonzalez, M.; Wetzel, J.; Wu, C.; Hu, X.; Prat, J.; Mudrock, E.; Hettinger, R.; Cortina, A.E.; Ghosh Biswas, R.; Kock, F.V.C.; Soong, R.; Jenne, A.; Du, B.; Hou, F.; He, H.; Lundeen, R.; Gilbreath, A.; Sutton, R.; Scholz, N.L.; Davis, J.W.; Dodd, M.C.; Simpson, A.; McIntyre, J.K.; Kolodziej, E.P. A ubiquitous tire rubber-derived chemical induces acute mortality in Coho salmon. Science 2021, 371(6525), 185-189.

Wu, B.; Majumdar, R.D.; Lysak, D.; Ghosh Biswas, R.; Tabatabaei-Anaraki, M.; Jenne, A.; You, X.; Soong, R.; Lane, D.; Helm, P.A.; Codina, A.; Decker, V.; Simpson, M.J.; Simpson, A. Towards real-time kinetic monitoring of wastewater treatment: A case study of sunlight and ozone treatment of unconcentrated wastewater using flow NMR. Chemical Engineering Journal. 2021, 405, 126696.

Soong, R.; Jenne, A.; Ghosh Biswas, R.; Adamo, A.; Simpson, A. Exploring the maker culture in chemistry: Making an affordable thermal imaging system for reaction visualization. Journal of Chemical Education. 2020, 97(10), 3887-3891.

Ghosh Biswas, R.; Fortier-McGill, B.; Akhter, M.; Soong, R.; Ning, P.; Bastawrous, M.; Jenne, A.; Schmidig, D.; De Castro, P.; Graf, S.; Kuehn, T.; Busse F.; Struppe, J.; Fey, M.; Heumann, H.; Boenisch, H.; Gundy, M.; Simpson, M.J.; Simpson, A. Ex vivo comprehensive multiphase NMR of whole organisms: A complementary tool to in vivo NMR. Analytica Chimica Acta: X. 2020, 6, 100051.

Soong, R.; Jenne, A.; Pautler, B.; Moser, A.; Adamo, A.; Simpson A. A CASE (computer assisted structure elucidation) study for an undergraduate organic chemistry class. Journal of Chemical Education. 2020, 97(3): 855-860.

Wu, B.; von der Ecken, S.; Swyer, I.; Li, C.; Jenne, A.; Vincent, F.; Schmidig, D.; Kuehn, T.; Busse, F.; Stronks, H.; Soong, R.; Wheeler, A.H.; Simpson, A.J. Rapid chemical monitoring by digital microfluidics-NMR: Proof of principle towards an automated synthetic discovery platform. Angewandte Chemie International Edition. 2019, 58(43): 15372-15376.

Soong, R.; Agmata, K.; Doyle, T.; Jenne, A.; Adamo, T.; Simpson A. Rethinking a timeless titration experimental setup through automation and open-source robotic technology - making titration accessible for all students of all abilities. Journal of Chemical Education. 2019, 96(7), 1497-1501.

Tabatabaei-Anaraki, M.; Lane, D.; Bastawrous, M.; Jenne, A.; Simpson, A.J. Metabolic profiling using in-vivo high field flow NMR. NMR-based Metabolomics: Methods and Protocols, Springer. 2019, 2037, 395-409.

Swyer, I.; von der Ecken, S.; Wu, B.; Jenne, A.; Soong, R.; Vincent, F.; Schmidig, D.; Frei, T.; Busse, F.; Stronks, H. J.; Simpson, A. J.; Wheeler, A. R. Digital microfluidics and nuclear magnetic resonance spectroscopy for in situ diffusion measurements and reaction monitoring. Lab on a Chip. 2019, 19, 641-653.

Jenne, A.; Soong, R.; Bermel, W.; Sharma, N.; Masi, A.; Tabatabaei-Anaraki, M.; Simpson, A. Focusing on “the important" through targeted NMR experiments: An example of selective ¹³C-¹²C bond detection in complex mixtures. Faraday Discussions. 2018, 218, 372-394.

Soong, R.; Agmata, K.; Doyle, T.; Jenne, A.; Adamo, T.; Simpson, A. Combining the maker movement with accessibility needs in an undergraduate laboratory: A cost-effective text-to-speech multipurpose, universal chemistry sensor hub (MUCSH) for students with disabilities. Journal of Chemical Education. 2018, 95, 2268-2272.

Bastawrous, M.*; Jenne, A.*; Tabatabaei-Anaraki, M.; Simpson, A. In-Vivo NMR Spectroscopy: A Powerful and Complimentary Tool for Understanding Environmental Toxicity. Metabolites. 2018, 8, 35-59.