How do proteins function?

How do proteins function?

Biomolecular “machines” are found throughout our cells, and are made up of single proteins or of groups of proteins. The diversity of these protein-based biomolecular machines is reflected how they work with cells. For example, proteins on the surface of the cell control molecules going in and out of the cell, while proteins inside the nucleus control how genes are turned on and off.

Research in the Department of Chemical and Physical Sciences investigates how proteins regulate biological processes, how proteins can go rogue and cause disease, and how we can fix these rogue proteins to treat diseases.

Virgis Barzda

Virgis Barzda

Studies how thousands of nanomotors synchronize to produce muscle cell contraction and how collagen fibers mediate cancer cell metastases.

Andrew Beharry

Andrew Beharry

Constructs small molecule probes to udnerstand and treat various types of cancer.

Claudiu Gardinaru

Claudiu Gradinaru

Uses single-molecule fluorescence spectroscopy to reveal conformations, interactions and dynamics of intrinsically disordered proteins and GPCR receptors.

Josh Milstein

Joshua Milstein

Builds single-molecule tools to study the cellular organization and dynamics of proteins and nucleic acids.

Scott Prosser

Scott Prosser

Uses NMR Spectroscopy to understand protein folding and misfolding, how enzymes function, and the dynamics of GPCR receptors.

Sarah Rauscher

Sarah Rauscher

Applies computational biophysics to understand the atomistic structure and dynamics of intrinsically disorderd proteins.