Majid Ghareghani
Title/Position
Postdoctoral Fellow
Ghorbani Lab
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E-mail:
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Mailing Address:
3359 Mississauga Road
Mississauga ON L5L1C6
Canada
Research Interests
Driven by a passion for neuroimmunology, he initially focused on the therapeutic potential of the innate immune system in neurodegenerative diseases during his postdoctoral research in Dr. Serge Rivest’s laboratory at CHU de Québec – Université Laval. He explored novel innate immune-based strategies to promote cerebrovascular amyloid-beta clearance in Alzheimer's disease.
Then, he joined Dr. Samira Ghorbani’s laboratory to pursue a new postdoctoral project aimed at repairing demyelination damage in multiple sclerosis. His current research particularly emphasizes aging-related changes in oligodendrocytes and strategies to rejuvenate myelination capacity in the aging central nervous system.
Then, he joined Dr. Samira Ghorbani’s laboratory to pursue a new postdoctoral project aimed at repairing demyelination damage in multiple sclerosis. His current research particularly emphasizes aging-related changes in oligodendrocytes and strategies to rejuvenate myelination capacity in the aging central nervous system.
Recent Publications
His full list of publications can be found on his PubMed profile or Google Scholar profile.
- Ghareghani M, Arneaud A, Rivest S. The evolution of mesenchymal stem cell-derived neural progenitor therapy for Multiple Sclerosis: from concept to clinic. Front Cell Neurosci. 2024.
- Ghareghani M, Rivest S. The Synergistic Potential of Combining PD-1/PD-L1 Immune Checkpoint Inhibitors with NOD2 Agonists in Alzheimer's Disease Treatment. Int J Mol Sci. 2023.
- Ghareghani M et al. Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis. Exp Mol Med. 2023.
- Ghareghani M et al. Melatonin and vitamin D, two sides of the same coin, better to land on its edge to improve multiple sclerosis. Proc Natl Acad Sci USA. 2023.