Inactivation of a low temperature-induced RNA helicase in Synechocystis sp. PCC 6803: Physiological and morphological consequences

This week we recognize the work of former BIO 481 student Meghana Ventakesh from the Espie Lab.

In collaboration with the Owttrim lab from U Alberta, Meghana recently published her work in Plant and Cell Physiology. This paper examines the molecular and physiological mechanisms by which cyanobacteria respond to cold temperatures. Specifically, the inability of a mutant line to grow at cold temperatures was directly related to the cessation of photosynthesis caused by a DEAD box helicase. Mutants lacking this helicase had reduced capacity for electron transport that limited the supply of ATP and NADPH for carbon fixation, eventually causing cell death.

Meghana recently finished a degree in our M.Biotech Program. Congratulations, Meghana!

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