January 23, 2025 Seminar - Dr. Massimo Scanziani

Massimo Scanziani

Dr. Massimo Scanziani

Professor, Howard Hughes Medical Institute Investigator, UCSF School of Medicine

PI: Prof. Baohua Liu

12 to 1 PM
IB 140 & Zoom

Title

Simulated Actions in the Virtual World of REM Sleep

Abstract

I will present large scale recordings performed in the brain of mice during REM sleep, a phase of sleep associated with vivid simulations we call dreams. I will show that during this phase of sleep, the activity of various brain regions is coordinated in a way that reminds us of the awake, behaving animal engaged with the external world. These observations reveal the ability of the sleeping brain to simulate actions by issuing motor commands and represent their consequences even when these motor commands are not executed. By performing large scale recordings from multiple brain regions during REM sleep we are starting to uncover the brain’s “internal model” of the world.

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