Areej Al Dailami picture, in the lab, wearing a labcoat

Areej Al-Dailami's Paper Published in “Woman in Insect Physiology, 2022

We are so proud of Areej Al-Dailami, PhD student, Lange Lab, as her paper was published by Frontiers in Insect Physiology, in a special issue: “Woman in Insect Physiology, 2022

Investigating the role of glycoprotein hormone GPA2/GPB5 signaling in reproduction in adult female Rhodnius prolixus

"There is limited research on the physiological roles of the recently discovered glycoprotein hormone GPA2/GPB5 in invertebrates, and our goal is to understand how this hormone might contribute to successful egg production in the kissing bug, Rhodnius prolixus. Our results indicate a novel role for this hormone in adult female R. prolixus, with the GPA2/GPB5 signaling pathway acting to delay egg production. Thus, disruption of this pathway by RNAi leads to accelerated oogenesis, an increase in the number of eggs produced and laid, an increase in egg size and a reduction in hatching rate. RNAi delivered by the genetic modification of R. prolixus gut microbiota has the potential to curb vector transmission by R. prolixus, and targeting the GPA2/GPB5 signaling pathway may well be a fruitful line of research to pursue." noted Al-Dailami



pic from Areej's paper


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