Dr. Sergey Kryazhimskiy
Associate Professor
University of California, San Deigo, Department of Ecology, Behaviour, & Evolution
PI: Prof. Alex Nguyen
12 to 1 PM
IB 140 & Zoom
Title
Abstract
Adaptive evolution can lead to profound changes in the phenotypes and behaviors of biological systems, with adverse or beneficial consequences. However, predicting these changes remains difficult. One major challenge is that how new mutations alter phenotypes and fitness of organisms often depends on the genetic background in which they arise (G×G interactions or “epistasis”), the environment (G×E interactions), or both (G×G×E interactions). In this talk, I will discuss our recent experimental efforts to measure these interactions in budding yeast and some implications of our findings for evolutionary dynamics.