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Joshua N. Milstein
Associate Professor

Dept. of Physics, University of Toronto
Dept. of Chemical and Physical Sciences, UTM
Institute of Biomaterials and Biomolecular Engineering (IBBME)
Office: DV 4053
Phone: (905) 569-4598
Email: josh.milstein@utoronto.ca
Postdocs and Research Assistants
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Emiel Visser
Marie-Curie Postdoctoral Fellow

Rm: DV5032
Ph: (905) 828-5436

"I study the mechanism by which H-NS and similar nucleic acid associated proteins (NAPs) silence gene transcription. I use a combination of optical tweezers and tethered particle motion analysis to observe the transcription process of single DNA molecules under a variety of condition. NAPs such as H-NS play an important role in the spread of antibiotic resistance in enteric bacteria, and by understanding the mechanism behind these proteins we aim to prevent or revert the spread of antibiotic resistance genes between bacteria."
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Daniel Djayakarsana
Research Assistant

Rm: DV5032
Ph: (905) 828-5436

"With the advent of faster (and cheaper!) computing technologies, a new era of software research is now accessible to any lab, no supercomputer required. Currently, there are gaps in fast 3D clustering algorithms for super-resolution and my goal is to benchmark and generalize our group's algorithm, called FOCAL, to the third spatial dimension."
Graduate Students
Nafiseh Rafiei
PhD Student
Biomedical Engineering, IBBME

Rm: DV5032
Ph: (905) 828-5436

"The focus of my PhD project is to study the spatial redistribution H-NS as well as the chromosome in E. coli in response to the environmental stresses, especially osmotic stress, using super-resolved microscopy. By this study, we can understand better the underlying mechanism of bacteria response to environmental changes."
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Smiley face Daniel Nino
PhD Student
Physics

Rm: DV5032
Ph: (905) 828-5436

"Super-Resolution Localization microscopy (SRLM) has revolutionized cellular biology by surpassing the diffraction limit of conventional fluorescence microscopy. Recent years have seen a shift from using SRLM primarily for qualitative-focused studies to integrating quantitative-focused studies. I am developing novel statistical approaches in quantitative localization microscopy to tackle the molecular counting problem using organic photoswitchable fluorophores."
Zheng Zhang
MSc Student
Physics

Rm: DV5032
Ph: (905) 828-5436

"I got my BSc degree from Beijing Normal University and came here for the MSc program. My work is mainly on the optical tweezers, including the development of the technology and the biological experiments related to nucleoid associated proteins. As for my hobby, I enjoy walking around the city during the weekend to experience the diverse culture."
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Smiley face Tianyi Ma
MSc Student
Physics

Rm: DV5032
Ph: (905) 828-5436

Bacterial competition and microfluidics
Undergraduate Students
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Faiyza Alam
Physics
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Minah Tariq
Biology
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Kasha
Physics
Former Members
Graduate Students
Samuel Yoshua (Physics, MSc Student, 2016)
Russell Pollari (Physics, MSc Student, 2015)
Stephen Havlick (Physics, MSc Student, 2015)
Tai-Wei Su (Bioengineering MSc Student, NCKU Taiwan, 2014)
Anastasia Zaytseva (Applied Math, MSc Student, 2013)

Postdocs and Technicians
Dr. Amir Mazouchi (Postdoc, 2014-2017)
Dr. Yong Wang (HFSP Postdoc, 2014-2016): Assistant Professor, Department of Physics, University of Arkansas
Dr. Haowei Wang (Postdoc, 2012-2015): Assistant Professor, University of Science and Technology (USTC), China
Abdullah Bahram (Laboratory Technician, 2012-2013)

Undergraduates
Danica Jovanovich (Physics, 2017)
Daniel Gorelick (Chemistry, 2016/2017) / Hector He (Physics, 2017) / Shabeeh Rizvi (Physics, 2017)
Paul Penkul (Biology, 2015/2016) / Danielle Sims (Physics, 2016) / Paul Lelay (Physics, 2016)
Emily Storey (Physics, 2015/2016) / Aoife Taylor (Chemistry, Cardiff University, 2016)
Shubham Mistry (Biology, 2016) / Rachel Hanke (Biology, 2016) / Phuong Julia Le (Computer Science, 2015)
Thurga Rajeswaran (Biology, 2015) / Ezra Sebastian Hartono (Physics, 2015)
Muhammad Ahmed (Chemistry, 2014) / Mejd Jumaily (Biology, 2014) / Daniel Nino (Physics, 2014)
Alexandra Derla (CCIT, 2014) / Stela Ishitani Silva (Physics, SWB Brazil, 2014)
Marcelo Augusto Cordeiro (Computer Science, SWB Brazil, 2014) / Nanak Singh (Chemistry, Cardiff University, 2014)
Mark DeBenedetti (Physics, 2014) / Roger Bialy (Chemistry, 2013)
Taise Lima (Biotechnology, SWB Brazil, 2013) / Surya Buss (Biotechnology, SWB Brazil, 2013)
Stephen Havlick (Physics, 2013) / Mark Levy (Chemistry, 2012)
Jia Chen (Biology, 2012) / Wendy Otieno (Physics, 2012)
Collaborators
William W. Navarre, Department of Molecular Genetics, University of Toronto
Jennifer Mitchell, Department of Cell and Systems Biology, University of Toronto
Anton Zilman, Department of Physics, University of Toronto
SafeGuard Biosystems, Toronto, ON, CAN