Our lab focuses on studying the dynamical motion of DNA, which, while being intimately involved in genetic function, has operational effects that are not well understood at present. Errors in genetic expression, besides arising from mistakes in the code itself, could also manifest by macromolecules that over-twist or over-stretch the DNA, problems in packing within the nucleus, long-range interference between genes, and so on. Studying the dynamics of DNA, while challenging, has the potential to define a new paradigm for our understanding of cellular function, which could have a range of implications for our understanding of health and disease.

NEWS (20/01/15): A number of ROP positions are available for undergraduates in both the Summer and Fall of 2015. Visit the ROP website for more information.

NEWS (01/02/15): We have a position available for a graduate student to start in the Summer/Fall of 2015. Please send an email to Dr. Joshua Milstein .