Yang, Guojun

Assistant ProfessorBiology

Contact Information

Phone: 
(905) 569-4751
Fax: 
(905) 828-3792
Room: 
DV 3035
Guojun Yang

Research

Transposable elements (TEs) form a major community in eukaryotic genome ecosystems, where they often account for at least half of total content. The discovery of transposons has forced biologists to view genomes as much more dynamic systems than previously imagined. In addition, TE derived DNA tools are widely used in mutagenesis (gene discovery), genetic mapping (markers) and transgenesis. The most intriguing issues surrounding TEs are their interaction with host genome and their persistent proliferation during evolution despite being mutagens. Our research aims to understand how transposable elements shape genome function and evolution.

 

Publications

  • Janicki, M., Rooke, R.  and Yang, G. 2011. Bioinformatics and Genomic Analysis of Transposable Elements in Eukaryotic Genomes. Chromosome Research (Invited review, In press)
  • Hu, T., He, S., Yang, G., Zeng, H., Wang, G., Chen, Z., Huang, X. 2011. Isolation and characterization of a rice glutathione S-transferase gene promoter regulated by herbicides and hormones. Plant Cell Rep. 30, 539-549. DOI 10.1007/s00299-010-0964-z
  • Rooke, R and Yang, G. 2011. TE Displayer for post-genomic analysis of transposable elements. Bioinformatics, 27(2):286-287. DOI 10.1093/bioinformatics/btq639
  • Yang, G. Nagel, D.H., Feschotte, C., Hancock, C.N. and Wessler, S.R.2009. Tuned for transposition: molecular determinants underlying the hyperactivity of a Stowaway MITE. Science 325, 1391-1394. (Featured in Science and Cell).
  • Yang, G., Zhang, F. and Wessler, S.R. 2007. Transposition of the rice MITE mPing in Arabidopsis. PNAS, 104: 10962-10967.
  • Yang, G., Weil, C.F. and Wessler, S.R. 2006. Transposition of a rice Tc1/mariner-like element in yeast. Plant Cell 18: 2469-2478.
  • Tuskan, G. et al. The genome of black cottonwood, Populus trichocarpa (Torr. & Gray ex Brayshaw). 2006. Science 313: 1596-1604